Posaconazole (SCH 56592)

規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
10 mg	3-5days	￥450.00	登錄后可見(jiàn)	- +
25 mg	3-5days	￥650.00	登錄后可見(jiàn)	- +
50 mg	3-5days	￥950.00	登錄后可見(jiàn)	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

10 mg

3-5days

￥450.00

登錄后可見(jiàn)

- +

25 mg

3-5days

￥650.00

登錄后可見(jiàn)

- +

50 mg

3-5days

￥950.00

登錄后可見(jiàn)

- +

基本信息

英文名稱	Posaconazole (Synonyms: SCH 56592; 泊沙康唑;)
中文名稱	4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-三唑-1-基)甲基)-5-(2,4-二氟苯基)四氫呋喃-3-基)甲氧基)苯基)哌嗪-1-基)苯基)-1-((2S,3S)-2-羥基戊-3-基)-1H-1,2,4-三唑-5(4H)-酮
CAS號(hào)	171228-49-2
分子式	C37H42F2N8O4
分子量	700.78
MDL	MFCD00941162
外觀	White to off-white powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

安全信息

產(chǎn)品詳情

Posaconazole (also known as SCH 56592 or trade name of Noxafil) is a potent,broad-spectrum, second generation triazole antifungal compound that potently inhibits 14α-demethylation in a variety of fungi, including Candida and Aspergillus, with half maximal inhibition concentration IC50 of 0.007 μg/ml, 0.06 μg/ml, 0.2 μg/ml, 0.3 μg/ml, 0.03 μg/ml and 0.03 μg/ml respectively Posaconzole, an itraconzole derivative with fluorine replacing chlorine in the phenyl ring and hydroxylation in the side chain, binds to the heme cofactor on the active site of 14α-demethylase, which converts lanosterol to 14α-dimethy lanosterol, resulting in the disruption of the integrity and function of the fungal cell membrane and inhibition of fungal growth.

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CL2521

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-三唑-1-基)甲基)-5-(2,4-二氟苯基)四氫呋喃-3-基)甲氧基)苯基)哌嗪-1-基)苯基)-1-((2S,3S)-2-羥基戊-3-基)-1H-1,2,4-三唑-5(4H)-酮

171228-49-2 98+% 3-5days

￥450.00 10 mg

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4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-三唑-1-基)甲基)-5-(2,4-二氟苯基)四氫呋喃-3-基)甲氧基)苯基)哌嗪-1-基)苯基)-1-((2S,3S)-2-羥基戊-3-基)-1H-1,2,4-三唑-5(4H)-酮

Posaconazole (Synonyms: SCH 56592; 泊沙康唑;)

化學(xué)品安全說(shuō)明書(MSDS)